Moca cognitive test cutoff scores
Further refinements to the aMCI diagnostic criteria include the differentiation of those whose impairments are only in the memory domain (single domain) versus those who are impaired in memory and another cognitive domain (multiple domain) ( Petersen and Negash, 2008). However, the aMCI diagnosis is made only after an extensive neuropsychological examination which prevents the diagnosis from being made in general practice settings where cognitive screening measures are often used to determine if an individual requires a more comprehensive cognitive assessment ( Townley et al., 2019). The diagnostic criteria for aMCI have remained largely the same since their initial publication ( Petersen et al., 1999) and require that an individual’s episodic memory performance fall at least 1.5 standard deviations below what would be expected for their age and education level and is accompanied by a self-reported or collateral-reported complaint of cognitive decline. While not all individuals with aMCI progress to AD, they are thought to be at the highest risk of progression and this classification is often referred to as “MCI due to AD” ( Albert et al., 2011 Sperling et al., 2011). The findings of this meta-analysis also support the use of 24 as the optimal cutoff when the MoCA is used to screen for suspected cognitive impairment.Īmnestic mild cognitive impairment (aMCI) due to Alzheimer’s disease (AD) is a syndrome that is associated with future progression to clinical AD. The median cutoff score for identifying aMCI was <24.ĭiscussion and conclusion: The MoCA has good diagnostic accuracy for detecting aMCI across several different languages. Both analyses had high levels of between-study heterogeneity. The overall AUC value was 0.84 (95% CI: 0.81, 0.87) indicating good diagnostic accuracy and a large effect size was noted for the SMD analysis (Hedge’s g = 1.49, 95% CI: 1.33, 1.64). Thirty-nine studies were used in the AUC analysis while 44 were used in the SMD analysis. Results: Fifty-five observational studies that included 17,343 CU and 8,413 aMCI subjects were selected for inclusion. Meta-analyses for area under the curve (AUC) and standardized mean difference (SMD) values were performed. Methods: PubMed and EMBASE databases were searched from inception to 22 February 2022. The aim of this study was to summarize the diagnostic accuracy and mean difference of the MoCA when comparing cognitively unimpaired (CU) older adults to those with amnestic mild cognitive impairment (aMCI). Although the original validation study suggested to use a cutoff of ≤26, subsequent studies have shown that lower cutoff values may yield fewer false-positive indications of cognitive impairment.
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2College of Medicine, University of Arizona, Phoenix, AZ, United Statesīackground: The Montreal Cognitive Assessment (MoCA) is one of the most widely-used cognitive screening instruments and has been translated into several different languages and dialects.1Banner Alzheimer’s Institute, Phoenix, AZ, United States.Michael Malek-Ahmadi 1,2 * † Nia Nikkhahmanesh 2